Professor in Orthopaedic Surgery
As an Orthopaedic Surgeon, Dr. Olson's primary focus of research is joint preservation. His primary clinical interests are Orthopaedic Trauma and Hip Reconstruction.
In Orthopaedic Trauma my research interests are: 1) Basic science investigations of articular fractures with two current animal models in use. 2) Clinical research includes evaluation of techniques to reduce and stabilize articular fractures, as well as management of open fractures.
In the area of Hip Reconstruction, my areas of research are 1) Hip Arthroscopy and treatment of hip disorders and treatment of labral tears in the treatment of hip pain. 2) Periacetabular osteotomy for the treatment of hip dysplasia.
Lab Achievements
Dr. Olson received the 2015 Kappa Delta Award from the Orthopaedic Research Society and American Academy of Orthopaedic Surgeons in recognition of his paper entitled, “Therapeutic Opportunities to Prevent Post-Traumatic Arthritis: Lessons from the Natural History of Arthritis after Articular Fracture.” The 2015 Ann Doner Vaughn Award was presented to Dr. Steven A. Olson and his colleagues, Bridgette Furman, Virginia Kraus, Janet Huebner, and Farshid Guilak. This Kappa Delta award recognizes innovative basic science orthopaedic research. Read more about this prestigious award here.
Selected Publications and Grants
Publications
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Buchanan, Michael W., Bridgette D. Furman, Amy L. McNulty, and Steven A. Olson. “Combination of Lidocaine and IL-1Ra Is Effective at Reducing Degradation of Porcine Cartilage Explants.” Am J Sports Med 50, no. 7 (June 2022): 1997–2006. https://doi.org/10.1177/03635465221090611.
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Cheah, Jonathan W., Richard Danilkowicz, Carolyn Hutyra, Brian Lewis, Steve Olson, Emily Poehlein, Cynthia L. Green, and Richard Mather. “High Prevalence of Sleep Disturbance Is Associated with Femoroacetabular Impingement Syndrome.” Arthrosc Sports Med Rehabil 4, no. 2 (April 2022): e495–501. https://doi.org/10.1016/j.asmr.2021.11.008.
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Allen, Nicholas B., Bijan Abar, Richard M. Danilkowicz, Virginia B. Kraus, Steven A. Olson, and Samuel B. Adams. “Intra-Articular Synovial Fluid With Hematoma After Ankle Fracture Promotes Cartilage Damage In Vitro Partially Attenuated by Anti-Inflammatory Agents.” Foot Ankle Int 43, no. 3 (March 2022): 426–38. https://doi.org/10.1177/10711007211046952.
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COVIDSurg Collaborative, Peter E. “Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.” Br J Surg 108, no. 11 (November 11, 2021): 1274–92. https://doi.org/10.1093/bjs/znab183.
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COVID Surg Collaborative, A. T. L. A. S. “Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection.” Bjs Open 5, no. 6 (November 9, 2021). https://doi.org/10.1093/bjsopen/zrab131.
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Vovos, Tyler J., Bridgette D. Furman, Janet L. Huebner, Kelly A. Kimmerling, Gangadhar M. Utturkar, Cynthia L. Green, Virginia B. Kraus, Farshid Guilak, and Steven A. Olson. “Initial displacement of the intra-articular surface after articular fracture correlates with PTA in C57BL/6 mice but not "superhealer" MRL/MpJ mice.” J Orthop Res 39, no. 9 (September 2021): 1977–87. https://doi.org/10.1002/jor.24912.
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Buchanan, Michael W., Bridgette D. Furman, Jacob H. Zeitlin, Janet L. Huebner, Virginia B. Kraus, John S. Yi, and Steven A. Olson. “Degenerative joint changes following intra-articular fracture are more severe in mice with T cell deficiency.” J Orthop Res 39, no. 8 (August 2021): 1710–21. https://doi.org/10.1002/jor.24899.
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Cardiothoracic Interdisciplinary Research Network and COVIDSurg Collaborative, Jean. “Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study.” J Thorac Cardiovasc Surg 162, no. 2 (August 2021): e355–72. https://doi.org/10.1016/j.jtcvs.2021.03.091.
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George, Steven Z., Xiaofang Yan, Sheng Luo, Steven A. Olson, Emily K. Reinke, Michael P. Bolognesi, and Maggie E. Horn. “Can PROMIS measures be used to create subgroups for patients seeking orthopaedic care?” Bone Jt Open 2, no. 7 (July 2021): 493–502. https://doi.org/10.1302/2633-1462.27.BJO-2021-0045.R1.
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Furman, B. D., J. H. Zeitlin, M. W. Buchanan, J. L. Huebner, V. B. Kraus, J. S. Yi, S. B. Adams, and S. A. Olson. “Immune cell profiling in the joint following human and murine articular fracture.” Osteoarthritis Cartilage 29, no. 6 (June 2021): 915–23. https://doi.org/10.1016/j.joca.2021.02.565.
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Grants
- Validation of novel serum, and synovial fluid proteomic biomarkers as potential predictors of post-traumatic osteoarthritis after intraarticular ankle fractures (Principal Investigator), awarded by Piedmont Orthopedic Foundation, administered by Orthopaedics, 2021-2022 More info
- Characterization of porcine synovial cells in co-culture (Principal Investigator), awarded by Piedmont Orthopedic Foundation, administered by Orthopaedics, 2020-2020 More info
- Fresh Tissue Agreement (Principal Investigator), awarded by DePuy Synthes Companies, administered by Orthopaedics, 2019-2019 More info
- Fresh Tissue Agreement (Principal Investigator), awarded by Zimmer Biomet Company, administered by Orthopaedics, 2018-2018 More info
- PROSPECTIVE, RANDOMIZED, CONTROLLED, MULTICENTER, MULTI-NATIONAL, PIVOTAL, CLINICAL INVESTIGATION EVALUATING THE SAFETY AND EFFICACY OF HEMOBLASTTM BELLOWS IN CARDIOTHORACIC, ABDOMINAL, AND ORTHOPEDIC LOWER EXTREMITY SURGERIES (Principal Investigator), awarded by Biom'Up, administered by Orthopaedics, 2016-2017 More info
- Investigation into the Injury Response to Articular Cartilage (Principal Investigator), awarded by DePuy Synthes Companies, administered by Orthopaedics, 2015-2016 More info
- Live-Animal Micro-CT System (Major User), awarded by National Institutes of Health, administered by Orthopaedics, 2012-2014 More info
- Fresh Tissue Lab Agreement (Principal Investigator), awarded by Southeastern Fracture Consortium Foundation, administered by Orthopaedics, 2014-2014 More info
- Fresh Tissue Lab Agreement (Principal Investigator), awarded by Pivot Medical, Inc., administered by Orthopaedics, 2013-2013 More info
People
- Steven A. Olson, MD, Principal Investigator
- Bridgette D. Furman, BS, Research Analyst II
- Kelly A. Kimmerling, PhD Candidate, Advisor: Farshid Guilak
- Daniel Cunningham, Medical Student, Duke University Medical School
Team Olson Alumni (Students, Staff, and Visiting Scholars)
- Jens Strand, 2004
- W. Chad Hembree, 2004-2005
- Benjamin Ward, 2005-2006
- Troy Swimmer, 2006-2008
- Dennis Cattel, 2006-2007
- John S. Lewis, 2008-2009
- Jonathon Backus, 2008-2009
- Collin Kent, 2009-2011
- Evan Zeitler, 2009-2010
- Josef Stolberg-Stolberg, 2010-2011, 2012
- Daniel Mangiapani, 2010-2011
- Craig Louer, 2010-2011
- Philip Horne, 2011
- Minna Zhang, 2011
- Michael Moverman, 2011-2014
- Karsyn Bailey, 2010-2014
- Tyler Vovos, 2013-2014
Jobs
We are always looking for qualified individuals interested in orthopaedic research. Applications for undergraduate and medical students, post-doctoral fellows, and research staff positions will be considered.
Contact
Mailing Address
DUMC 3389, Durham, NC 27710
Our laboratory is located on the third floor of the Medical Science Research Building (MSRB) at Duke University Medical Center.
Address
375 Medical Sciences Research Building
Research Dr.
DUMC Box 3093
Duke University Medical Center
Durham, NC 27710 USA
Phone: 919-668-3000
Email: steven.olson@duke.edu